A Population Study Of Microcystic Corneal Epithelial Changes.

The purpose of this study is to do a population study to determine the prevalence of microcystic changes in a general clinical population. lt will also compare biomicroscopic examination techniques that do not require a dilated pupil with the technique used by Werblin, et al, in which all patients were dilated. This study compared retroillumination off of the iris and the tear break-up time test to find the microcystic cnanges. The basement membrane of the epitlhelium is abnormal and there is localized thickening of the epithelium in corneas with microcystic changes. Due to the fluroscein should run off of the affected areas of the cornea. This should produce a rapid symmetrical break-up time ( l-2 seconds), which
is repeatable.